i n f l a r x

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Pipeline

INFLAMMATION & IMMUNOLOGY (I&I)
Program
Preclinical
Phase 1
Phase 2
Phase 3
Market
Status & Milestones
hidradenitis suppurativa

Topline Phase 2a reported with Ph2b planning ongoing

chronic spontaneous urticaria

Topline Phase 2a reported

other immuno-dermatology

Additional indications in immuno-dermatology

broader I&I

Additional chronic indications including nephrology, hematology, neurology and others

CRITICAL CARE
Program
Preclinical
Phase 1
Phase 2
Phase 3
Market
Status & Milestones
critical COVID-19
SARS-CoV-2-induced ARDS

Approved by European Commission*

Broader ARDS

Phase 2 "Just Breathe" ASPR/BARDA clinical platform study

DERMATOLOGY
Program
Preclinical
Phase 1
Phase 2
Phase 3
Market
Status & Milestones
pyoderma gangrenosum

Phase 3 reported**

OTHER
Program
Preclinical
Phase 1
Phase 2
Phase 3
Market
Status & Milestones
Vilobelimab Life-cycle approach

For optimized use in chronic inflammatory indications

*Commercial partnering and distribution options in the EU being considered.
** Phase 3 stopped early for futility at interim analysis, FDA interaction considered.